Astrocytes make up half of the nerve cells that live in the brain. Although they are known to carry out essential tasks for the proper functioning of neurons, We analyzed three-dimensional images Astrocytes Amyloid Plaques of the brains of transgenic Alzheimer’s mice using physics-based mathematical functions. As we found, The astrocytes repelled each other, Typical toxic deposits of the disease. Apparently, The balance of these repulsive forces determined the final position of the astrocytes in the brain.
They discovered in mice with Alzheimer’s that astrocytes
We discovered this curiosity in collaboration with the groups of Bradley Hyman of Massachusetts General Hospital. In Boston and Eugene H. In the last twenty years, Hyman and Stanley have developed several projects based on the mathematical analysis. Of the symptoms of Alzheimer’s. Therefore, When we detect this spatial pattern in astrocytes, We soon turn to mathematicians to investigate the phenomenon. Rental Service business email list Undoubtedly, Collaboration between Astrocytes Amyloid Plaques neuroscientists and mathematicians plays an essential role today more than ever, As new technologies are generating an enormous amount of brain data that requires complex analyzes. We labeled astrocytes.
Implications of the finding
Research around the neurological treatment of Alzheimer’s disease has focused on amyloid beta plaques from two approaches. Decreasing the production of these protein aggregates or increasing their elimination. One could think of astrocytes and microglia. Our study suggests that astrocytes do not suppress plaques, So it would be more appropriate to increase the capacity of microglia or blood cells for this purpose. On the Sale Lead other hand, The existence of an exclusion space around astrocytes could shed light on how astrocytes are formed during. Brain development and how they act in adult life. Astrocytes Amyloid Plaques challenges is to discover, The substance or substances that allow, Astrocytes and beta amyloid plaques affects cognitive decline in Alzheimer’s disease.
